部分学术论文 共403篇
1. Zihua Li, Shujie Zhang, Yudian Zhang, Jin Chen, Fuqing Wu, Gang Liu*,
Guo-Qiang Chen*, Applications and Mechanism of 3-Hydroxybutyrate (3HB)
for Treatments of Colonic Inflammation and Carcinogenesis, 2021, submitted.
2. Xiduan Wei, Jingjia Ye, Yamen Pei, Chunting Wang, Hongzhen Yang, ingyuan Tian, Guangxu Si, Yao Ma*, Kun Wang*, Gang Liu*, Extracellular Vesicles from Colorectal Cancer Cell Promote Cancer Metastasis via the NOD1 Signaling Pathway, submitted.
3. Xueyuan Li, Pengfei Geng, Xiaoqiao Hong, Zhaogang Sun, Gang Liu*,
Detecting and tracking Replicating and Non-replicating Mycobacterium
Tuberculosis in Host Cells with Rv2466c-Dependent Fluorescent Probe, 2021,
submitted.
4. Pengfei Geng, Xueyuan Li, Xiaoqiao Hong, Zhaogang Sun, Gang Liu*, Synthetic Calanolide Derivatives Using For Detecting Replicating and Non replicating Mycobacterium tuberculosis in Host Cell, 2021, manuscript in
preparing.
5. Yao Ma, Xue-Peng Zhang, Wenjun Yu, Xueyuan Li, Zijie Liu, Yi Dong,*
Gang Liu*, Palladium-Catalyzed Heck-Type Fluorination of Pyridyl Aldoximes, 2021, manuscript in preparing.
6. Brice A P Wilson, Donna Voeller, Emily A Smith, Antony Wamiru, Ekaterina
I Goncharova, Gang Liu, Stanley Lipkowitz, Barry R O'Keefe , In Vitro Ubiquitination Platform Identifies Methyl Ellipticiniums as Ubiquitin Ligase
Inhibitors, SLAS Discov. 2021, 24725552211000675. doi: 10.1177/24725552211000675.
7. Wenjun YU, Xilei Xie, Yao Ma, Shiping Fang, Yi Dong*, Gang LIU*,
Identification of 1,4-Denzodiazepine-2,5-dione Derivatives as Protein
Synthesis inhibitors with Highly Potent Anticancer Activities, manuscript in
preparing.
8. Wenju Yu, Yao Ma, Xilei Xie, Gang Liu*, Deuteration of, 4-benzodiazepine-
2,5-dione derivatives significantly improved cancer therapeutic potency in vivo, manuscript in preparing.
9. Chunting Wang, Yameng Pei, Lei Wang, Ye Xiang, Yao Ma*, Gang Liu*,
Constrain the Conformation: Discovery of (1H-pyrazolo[3,4-c]pyridin-5-
yl)sulfonamide Analogues as Hepatitis B Virus Capsid Assembly Modulator, J.
Med. Chem., 2020, 63, 6066-6089.
10. Yao Ma, Dawei Yin, Hai Qian*, Gang Liu*, Discovery of potent inhibitors
against P-glycoprotein-mediated multidrug resistance aided by late-stage
functionalization of 2-(4-(pyridin-2-yl)phenoxy)pyridine analogue, J. Med.
Chem. 2020, 63, 5458-5476.
11. Qiang Wei, Yao Ma, Yi Dong* and Gang LIU*, Coordinating Cu(I) Catalyzed Site-selective Direct sp3C()-H Alkoxylation via the SET Oxidation to form Quaternary -Alkoxylated -Amino Acid Derivatives, Org. Lett. 2020, 22, 5796-5800.
12. Yao Ma, Xueyuan Li, Yi Dong*, Gang Liu*, Discovery of Benzofused Five-Ring Sultams as Dual NOD1/NOD2 Antagonists, Eur. J. Med. Chem. 204
(2020) 112575.
13. Yao Ma, Jingsu Yang, Xiduan Wei, Yi Dong*, Gang Liu*, Nonpeptidic
Quinazolone Derivatives as Dual Nucleotide-Binding Oligomerization
Domain-like Receptors 1/2 (NOD1/NOD2) Antagonists, E. J. Med. Chem. 207
(2020) 112723.
14. Xueyuan Li, Xiao Hu, Zijie Liu, Jingshu Yang, Yi Dong* and Gang Liu*,
Ruthenium oxidase catalysis for cascade C–H alkenylation/annulation of aryl
sulfonamides, J. Org. Chem. 2020, 85, 5916-5926.
15. Jingshu Yang, Xiao Hu, Zijie Liu, Xueyuan Li, Yi Dong*, and Gang Liu*,
Cp*CoIII-catalyzed formal [4+2] cycloaddition of benzamides to afford
quinazolinone derivatives, Chem. Commun., 2019, 55, 13840-13843, DOI:
10.1039/C9CC07173C.
16. Jie Wu, Ran Mu, Mingna Sun, Nan Zhao, Miaomiao Pan, Hongshuang Li, Yi
Dong, Zhaogang Sun, Jie Bai, Minwan Hu, Carl F. Nathan, Babak Javid*,
Gang Liu*, Derivatives of Natural Product Agrimophol as Disruptors of
Intrabacterial pH Homeostasis in Mycobacterium tuberculosis, ACS Infect.
Dis. 2019, 5(7), 1087-1104 (DOI: 10.1021/acsinfecdis.8b00325).
17. Ran Mu, Chengcheng Kong, Wenjun Yu, Hongyao Wang, Jie Wu, Xueyuan Li, Selin Somersan-Karakaya, Haitao Li, Zhaogang Sun*, Gang LIU*,
Nitrooxidoreductase Rv2466c-Dependent Fluorescent Probe for Mycobacterium tuberculosis Diagnosis and Drug Susceptibility Testing, ACS
Infect. Dis. 2019, 5(6), 949-961 (doi: 10.1021/acsinfecdis.9b00006).
18. Jie Wu, Ran Mu, Zi-Jie Liu, Shi-Chao Lu and Gang Liu*，Scalable total synthesis of a mycobactin T analogue utilizing a novel synthetic and rotection strategy, Organic Chemistry Frontiers, 2019, 6, 2467-2470, DOI: 10.1039/C9QO00502A.
19. Yameng Pei, Chunting Wang, Haijing Ben, Lei Wang, Yao Ma, Qingyan
Ma, Ye Xiang, Linqi Zhang*, and Gang Liu*, Discovery of New Hepatitis B
Virus Capsid Assembly Modulators by an Optimal High-Throughput Cell- Based Assay, ACS Infect. Dis. 2019, 5, 778−787 (the Challenges and
Opportunities in Hepatitis B, Research special issue. doi: 10.1021/ acsinfecdis.9b00030).
20. Bao R, Tian C, Zhang H, Wang Z, Dong Z, Li Y, Gao M, Zhang H, Gang
Liu,* and Yefeng Tang*, Total Syntheses of Asperchalasines A-E., Angew
Chem Int Ed Engl. 2018 ， 57(43): 14216-14220. doi: 10.1002/ anie.201808249.
21. Qiang Wei, Yao Ma, Li Li, Qingfei Liu, Zijie Liu, and Gang Liu*, Synthesis
of Quaternary α-Fluorinated α-Amino Acid Derivatives via Coordinating
Cu(II) Catalytic α-C(sp3)-H Direct Fluorination, Org. Lett., 2018, 20,
7100−7103(Highlight in Synfacts, 2019, 15(02), 0208).
22. Xiaoming Wen, Purong Zheng, Yao Ma, Yingye Ou, Weixin Huang, Shuo
Li, Shoujia Liu, Xuan Zhang, Ziyu Wang, Qianli Zhang, Wenming
Cheng, Ruwen Lin, Hongzu Li, Youyou Cai, Chunyun Hu, Ningbin Wu, Long
Wan, Tingting Pan, Jinlong Yao, Xuelu Bei, Wei-Bin Wu, Jian Jin, Jie Yan*,
and Gang Liu*, Salutaxel, a conjugate of docetaxel and a muramyl dipeptide
(MDP) analogue, acts as multi-functional prodrug that inhibits tumor growth
and metastasis, J. Med. Chem. 2018, 61, 1519-1540.
23. Ana Negri, Prisca Javidnia, Ran Mu, Xiaojie Zhang, Jeremie Vendome, Ben
Gold, Julia Roberts, Dipti Barman, Thomas Ioerger, James Sacchettini, Xiuju
Jiang, Kristin Burns-Huang, Thulasi Warrier, Yan Lin, David Warren, Thijs
Beuming, Hongyao Wang, Jie Wu, Haitao Li, Kyu Rhee, Carl F. Nathan, Gang
Liu*, Selin Somersan-Karakaya*, Identification of a mycothiol-dependent
nitro-oxidoreductase from Mycobacterium tuberculosis, ACS Infect. Dis. 2018,
4, 771-787.（*co-senior authors）.
24. Da-Wei Yin, Gang Liu*, Palladium-Catalyzed Regioselective C-H
Functionalization of Arenes Substituted by Two N‑Heterocycles and
Application in Late-Stage Functionalization, J. Org. Chem. 2018, 83, 3987-
4001.
25. Bo Liu, Xue Liu, Jingren Zhang*, Gang Liu*, A Natural Lipotrisaccharide and Its Derivatives Selectively Lyse Streptococcus pneumoniae via Interaction with Cell Membrane, ACS Infect. Dis. 2017, 3, 438-453.
26. Yi Dong, Gang LIU*, Auxiliary-Assisted Palladium-Catalyzed Direct
C(sp3)−H Sulfonamidation To Afford 1,2-Amino Alcohol Derivatives. J. Org.
Chem. 2017, 82, 3864-3872.
27. Suhua Wang, Jingshu Yang, Xueyuan Li, Zijie Liu, Youzhen Wu, Guangxu
Si, Yiran Tao, Nan Zhao, Xiao Hu, Yao Ma*, Gang Liu*, Discovery of 1,4-
Benzodiazepine-2,5-dione (BZD) Derivatives as Dual Nucleotide Binding
Oligomerization Domain Containing 1 /2 (NOD1/NOD2) Antagonists
Sensitizing Paclitaxel (PTX) to Suppress Lewis Lung Carcinoma (LLC)
Growth In Vivo, J. Med. Chem. 2017, 60 (12), 5162-5192.(DOI:
10.1021/acs.jmedchem.7b00608)
28. Yi Dong, Suhua Wang, Chunting Wang, Zihua Li, Yao Ma*, Gang Liu*,
Antagonizing NOD2 Signaling with Conjugates of Paclitaxel and Muramyl
Dipeptide Derivatives Sensitizes Paclitaxel Therapy and Significantly Prevents
Tumor Metastasis, J. Med. Chem. 2017, 60, 1219-1224.
29. Maojin Li, Rouli Zhou*, Yi Shan, Li Li, Lin wang, Gang Liu*, Targeting a
novel cancer-driving protein (LAPTM4B-35) by a small molecule (ETS) to
inhibit cancer growth and metastasis, Oncotarget. 2016, 7(36), 58531-58542.
doi: 10.18632/oncotarget.11325.
30. Qidi Wang, Lianfeng Zhang, Kazuhiko Kuwahara, Li Li, Zijie Liu, Taisheng
Li, Hua Zhu, Jiangning Liu, Yanfeng Xu, Jing Xie, Hiroshi Morioka, Nobuo
Sakaguchi*, Chuan Qin*, Gang LIU*, Immunodominant SARS Coronavirus
Epitopes in Humans Elicited both Enhancing and Neutralizing Effects on
Infection in Non-Human Primates, ACS Infect. Dis. 2016, 2, 361-376. DOI:
10.1021/acsinfecdis.6b00006.
31. Chong Tian, Xiaoqiang Lei, Yuanhao Wang, Zhen Dong, Gang Liu* and
Yefeng Tang*, Total Syntheses of Periconiasins A–E, Angew. Chem. Int. Ed.
2016, 55, 6992-6995.
32. Zi-Jie Liu, Xiao-Yong Guo, Gang Liu*, Bioreductive calanolide analogues
against Mycobacterium tuberculosis, Chinese Chemical Letters 2016, 27(52),
51–54.
33. Zijie Liu, Youzhen Wu, Gang Liu*, Efficient and convenient total synthesis of mycothiol on a large scale, J. Chin. Pharm. Sci. 2015, 24(6), 347-355.
34. Nan Zhao, Mingna Sun, Kristin E. Burns-Huang, Xiuju Jiang, Yan Ling,
Crystal M. Darby, Sabine Erht, Gang Liu* and Carl F. Nathan*, Identification
of Rv3852 as an Agrimophol-Binding Protein in Mycobacterium tuberculosis,
PLoS One 2015, 10(5): e0126211. doi: 10.1371/journal.pone.0126211.
35. ZW Chen*, G Liu, XF Lu, L Liu, X Zhang, TCK Lau, SKW Tsui, YX Kang,
PR Zheng, BJ Zheng，Characterisation of novel anti-HIV/tuberculosis natural
product analogues，Hong Kong Med J 2015;21(Suppl 7): S14-7.
36. Qi-Fei Zhong, Rui Liu, and Gang Liu*, Structure-activity relationship studies on quinoxalin-2(1H)-one derivatives containing thiazol-2-amine against hepatitis C virus leading to the discovery of BH6870, Mol. Divers. 2015, 19: 829-853.
37. Xueyuan Li, Yi Dong, Fengyu QU*, Gang Liu*. Synthesis of benzofused five-ring sultams via Rh-catalyzed CH olefination directed by an N-Ac substituted sulfonamide group, J. Org. Chem. 2015, 80, 790−798.
38. Yi Dong, Nana Du, Xueyuan Li, Litao Zheng, Gang Liu*, Tandem
Chloropalladation/Cyclization and Dearomative Cyclization toward
Functionalized Tricyclic Bridged [3.2. 1] Skeleton Compounds, Org. Lett.
2015, 17(16):4110-3.
39. Zijie Liu, Xiaoyong Guo, and Gang Liu*, Modified calanolides incorporated
with furan-2-nitro mimics against Mycobacterium tuberculosis, Bioorg. Med.
Chem. Letts. 2015, 25, 1297-1300.
40. Xiao Hu, Yi Dong and Gang Liu*, Copper-catalyzed Ligand-free Amidation of Aryl iodides and Amino Acid Amides to Synthesize 3-(Z)-1H-benzo[e][1,4]diazepin-2(3H)-ones, Mol. Divers. 2015, 19: 695-701.
41. Leilei Zhang, Tianming Yang, Xilei Xie and Gang Liu*, Identification of 3, 5,
6-substituted indolin-2-one's inhibitors of Aurora B by development of a
luminescent kinase assay, Bioorg. Med. Chem. Letts. 2015(25) 2937-2942.
42. Purong Zheng, Selin Somersan Karakaya, Shichao Lu, Julia Roberts, Maneesh Pingle, Thulasi Warrier, David Little, Xiaoyong Guo, Steven Brickner, Carl F. Nathan*, Ben Gold*, Gang Liu*. Synthetic Calanolides with Bactericidal
Activity Against Replicating and Non-replicating Mycobacterium tuberculosiss, J. Med. Chem. 2014, 57(9), 3755–3772.
43. Hong-Shuang Li, Gang Liu*, Copper/Silver-Mediated Cascade Reactions for the Construction of 2-Sulfonylbenzo[b]furans from trans-2- Hydroxyc- innamic Acids and Sodium Sulfinates, J. Org. Chem. 2014, 79, 509−516.
44. Bo Liu, Fa Zhang, Yan Zhang, Gang Liu*, A new approach for the synthesis
of O-glycopeptides through a combination of solid-phase glycosylation and
fluorous tagging (SHGPFT), Org. Biomol. Chem. 2014, 12, 1892–1896.
45. Xilei Xie, Yu Yan, Ning Zhu, Gang Liu*, Benzothiazoles exhibit broad- spectrum antitumor activity: their potency, structure-activity and structure-metabolism relationships, Eur. J. Med. Chem. 2014, 76, 67-78.
46. Yaling Gong, Selin Somersan Karakaya, Purong Zheng, Ben Gold, David
Little, Julia Roberts, Thulasi Warrier, Xiuju Jiang, Maneesh Pingle, Carl F.
Nathan*, Gang Liu*, Benzimidazole-Based Compounds Kill Mycobacterium
tuberculosis, Eur. J. Med. Chem. 2014, 75, 336-353.
47. Xiaokang Li, Xinyong Zhang,a Zhao, Jingyu Wang, Gang Liu, and Yanan
Du*, Micro-scaffold array chip for upgrading cell-based high-throughput drug testing to 3D using benchtop equipment, Lab on a Chip 2014,14, 471-481.
48. Yingwei Hou, Shichao Lu and Gang Liu*, Iodine(III)-mediated [3+2]
cyclization for one-pot synthesis of benzo[d]isoxazole-4,7-diol, benzodiisoxazole-4,8-diol, isoxazole[5,4-a]phenazine and indazole-4,7-diol in aqueous medium, J. Org. Chem. 2013, 78, 8386−8395.
49. Yi Dong, Gang Liu*，Rh-Catalyzed Sulfonic Acid Group Directed C-H
Olefination of Arenes, Chem. Comm. 2013, 49, 8066-8068.
50. Yan Zhang, Bo Liu, Gang Liu*, Facile Synthesis of Tetrasaccharide Aided by
Fluorous Chemistry toward a Dengue Virus Vaccine, Mol. Divers. 2013, 17:
613–618.
51. Mingna Sun, Jinfeng Hu, Xiuyun Song, Donghui Wu, Linglei Kong, Yupeng
Sun, Dongmei Wang, Yan Wang*
, Naihong Chen*
and Gang Liu*
, Coumarin
Derivatives Protect Against Ischemic Brain Injury in Rats, Eur. J. Med. Chem.
2013, 67, 39-53.
52. Crystal M. Darby, Helgi I. Ingólfsson, Xiuju Jiang, Chun Shen, Mingna Sun,
Nan Zhao, Kristin Burns, Gang Liu, Sabine Ehrt, J. David Warren, Olaf S.
Anderson, Steven J. Brickner, and Carl Nathan*, Whole cell screen for
inhibitors of pH homeostasis in Mycobacterium tuberculosis, PLOS ONE
2013, 8(7), e68942.
53. Song XY, Hu JF, Sun MN, Li ZP, Wu DH, Ji HJ, Yuan YH, Zhu ZX, Han N,
Liu G, Chen NH*, IMM-H004, a novel coumarin derivative compound,
protects against amyloid beta-induced neurotoxicity through a mitochondrial-dependent pathway, Neuroscience 2013; 242:28-38.
54. Qun-yi LI, Ming-kai XU, Gang LIU, Claus Tornby CHRISTOFFERSEN,
Ming-wei WANG*, Discovery of novel PDE10 inhibitors by a robust
homogeneous screening assay, Acta Pharmacologica Sinica 2013: 1-5.
55. Yi Dong, Xiaoyong Guo, YuanYuan Yu and Gang Liu*, Highly
stereoselective synthesis of (Z)- and (E)-chloro-substituted--methylene--butyrolactone by possibly controlling cis- and trans-chloropalladation, Mol.
Divers. 2013, 17(1): 1-7.
56. Xiaoli Zhou, Xilei Xie, Gang Liu*, Quinazoline-2,4(1H,3H)-diones inhibit the growth of multiple human tumor cell lines, Mol. Divers. 2013, 17(2)：197-
219.
57. Xiao Yong Guo, Gang Liu*, Scaffold hopping strategy toward calanolides
with nitrogen-containing Heterocycles, Chinese Chemical Letters 2013, 24,
295–298.
58. Shichao Lu, Purong Zheng, Gang Liu, Iodine(III)-Mediated Tandem Oxidative Cyclization for Construction of 2-Nitrobenzo[b]furans, J. Org. Chem. 2012, 77, 7711-7717.
59. Nan Zhao, Yao Ma, Gang Liu, Solution-phase synthesis of a muramyl
dipeptide analogue MDA, Chinese Chemical Letters 2011, 22(12), 1443-46.)
60. Xiaofan Lu, Li Liu, Xu Zhang, Terrence Lau, Stephen Kwok-Wing Tsui,
Yuanxi Kang, Purong Zheng, Gang Liu* and Zhiwei Chen*, F18, a novel
small molecule NNRTI, inhibits HIV-1 replication using distinct binding
motifs, Antimicrob. Agents Chemother. 2012, 56(1): 341-351.
61. Yu Yan, Qifei Zhong, Nan Zhao, Gang Liu*, Cascade Mitsunobu reaction for the preparation of substituted 2-benzoxazole-N-phenyl and -benzimidazole-N-phenyl derivatives, Mol. Divers. 2012, 16, 157-162.
62. Rui Liu, Zhuhui Huang, Michael G. Murray, Xiaoyong Guo, Gang Liu*,
Quinoxalin-2(1H)-One Derivatives As Inhibitors Against Hepatitis C Virus, J.
Med. Chem. 2011, 54, 5747–5768.
63. Purong Zheng, Shichao Lu, Gang Liu*, An unexpected C–C cleavage reaction: new and mild access to o-OH and o-NH-Tos benzoic acids or benzoamides, Mol. Divers. 2011, 15:971–977.
64. Chunyan Han, Jinlan Zhang, Li Li, Mingyue Zheng, Yao Xiao, Yan Li*, Gang
Liu*. An integrated drug-likeness study for bicyclic privileged structures: from
physicochemical properties to in vitro ADME properties. Mol. Divers. 2011,
15:857–876.
65. Yu YAN, Jianjun ZHANG, Zijie LIU, Ruiming XU, Xiao HU, Gang LIU*, A
reversal method of diversity introduction of benzimidazole to synthesize
H+/K+-ATP enzyme inhibitors, Bioorg. Med. Chem. Lett. 2011, 21, 189-4192.
66. Nan Zhao, Yao Ma, Shengmei Zhang, Xin Fang, Zhenglun Liang, Gang Liu*, New muramyl dipeptide (MDP) mimics without the carbohydrate moiety as
potential adjuvant candidates for a therapeutic hepatitis B vaccine (HBV),
Bioorg. Med. Chem. Lett. 2011, 21, 4292-4295.
67. Yao Ma, Nan Zhao, Gang Liu*, Conjugate (MTC-220) of muramyl dipeptide analogue and paclitaxel prevents both tumor growth and metastasis in mice, J.Med. Chem. 2011, 54(8): 2767-77.
68. Ning Zhu, Fa Zhang, Gang Liu*, Dynamic Covalent Chemistry of Disulfides
Offers a Highly Efficient Synthesis of Diverse Benzofused Nitrogen-Sulfur
Heterocycles in One Pot. J. Combi. Chem. 2010, 12, 531-540.
69. Gang Li, Dongmei Wang, Mingna Sun, Guangyan Li, Jinfeng Hu, Yun Zhang, Yuhe Yuan, Haijie Ji, Naihong Chen*, Gang Liu. Discovery and
Optimization of Novel 3-Piperazinyl Coumarin Antagonist of Chemokine –
like factor 1 with oral Anti-asthma activity in mice. J. Med. Chem. 2010, 53
(4), 1741–1754.
70. Hai Xue, Xiaofan Lu, Purong Zheng, Li LIU, Chunyan Han, Jinping HU, Zijie
Liu, Tao MA, Yan LI, Lin WANG , Zhiwei CHEN*, Gang LIU*, Highly
suppressing wide type HIV-1 and Y181C mutation by 10-Chloromethyl-11-
Demethyl-12-oxo calanolide A with druggable profile. J. Med. Chem. 2010,
53, 1397–1401.
71. Chen YZ, Liu G, Senju S, Wang Q, Irie A, Haruta M, Matsui M, Yasui
F, Kohara M, Nishimura Y., Identification of SARS-COV spike protein-derived and HLA-A2-restricted human CTL epitopes by using a new muramyl
dipeptidederivative adjuvant., Int J Immunopathol Pharmacol. 2010, 23(1):
165-77.
72. Hai Xue, Tao Ma, Lin Wang, Gang Liu*, A new method for the synthesis of
N-substituted pyrroles, Chinese Chemical Letters 21 (2010) 1291-1294.
73. Hao Wu, Xilei Xie, Gang Liu*, Parallel Solution Phase Synthesis of
3,6,7−4(3H)-Quinazolinones and Evaluation of Their Antitumor Activities
against Human Cancer, J. Combi. Chem. 2010, 12, 346–355.
74. Leilei Zhang, Yu Yan, Zijie Liu, Abliz Zeper, Gang Liu*, Identification of
Peptide Substrate and Small Molecule Inhibitors of Testis-specific
Serine/Threonine Kinase1 (TSSK1) By the Developed Assays, J. Med. Chem.
2009, 52, 4419-4428.
75. Dongmei Wang, Mingna Sun, Gang Liu*, Substituent Diversity-Directed
Synthesis of Indole Derivatives, J. Combi. Chem. 2009, 11, 556–575.
76. Fa Zhang, Wei Zhang, Yan Zhang, Dennis P. Curran, and Gang Liu*,
Synthesis and Applications of Light-Fluorous Glycosyl Donor, J. Org. Chem.
2009, 74 (6), 2594-2597.
77. Tao MA, Li LIU, Hai XUE, Li LI, Chunyan HAN, Lin WANG, Zhiwei CHEN,
Gang LIU*, Chemical library and structure–activity relationships of 11-
demethyl-12-oxo calanolide A analogues as anti-HIV-1 agents, J. Med. Chem.2008, 51, 1432–1446.
78. Yu-Yan Chen, Wen-Yi He, Yan Wu, Chang-Qun Niu, and Gang Liu*,
Dynamic Selection of Novel Vancomycin N-Terminal Derivatives by Resin-bound Reversed D-Ala-D-Ala, J. Combi. Chem. 2008, 10, 914-922.
79. Xuqin Li, Junli Yu, Song Xu, Nan Wang, Hongzhen Yang, Zheng Yan,
Guifang Cheng, Gang Liu*, Chemical Conjugation of Muramyl Dipeptide and
Paclitaxel to Explore the Combination of Immunotherapy and Chemotherapy
for Cancer, Glycoconj. J. 2008, 25: 415–425.
80. Tao MA, Qi GAO, Zhiwei Chen, Lin WANG, Gang LIU*, Chemical
Resolutions of ()-Calanolide A, ()-Cordatolide A and Their 11-Demethyl
Derivatives, Bioorg. Med. Chem. Letts. 2008，18, 1079–1083.
81. Hai-Yan Zhao, Gang Liu*, Solution-Phase Parallel Synthesis of Diverse 1,5-Benzodiazepin-2-ones, J. Combi. Chem. 2007, 9, 1164 - 1176.
82. Li Li, Zhanguo Wang, Yuyan Chen, Yunyun Yuan, Guanxin Wang, Gang
Liu*, Design and Synthesis of Novel Tricyclic Compounds Based On 4H-Benzo[1,4]thiazin-3-one and 1,1-Dioxo-1,4-dihydro-2H-16-benzo[1,4]thiazin- 3-one, J. Combi. Chem. 2007, 9, 959-972.
83. Hai-Yan Zhao, Gang Liu*, Solution-Phase Synthesis of 2, 3-Dihydro-1,5-
benzothiazepin-4 (5H)-ones, J. Combi. Chem. 2007, 9, 756-772.
84. Zhanguo Wang, Yunyun Yuan, Yuyan Chen, Gangchun Sun, Xianghong Wu,
Shengmei Zhang, Chunyan Han, Guanxing Wang, Li Li, and Gang Liu*,
Parallel Solution-Phase Synthesis of 4H-Benzo[1,4]thiazin-3-one and 1,1-
Dioxo-1,4-dihydro-2H-1λ6-benzo[1,4]thiazin-3-one Derivatives from 1,5-
Difluoro-2,4-dinitrobenzene, J. Comb. Chem., 2007, 9 (4), 652–660.
85. Yunyun Yuan, Gang Liu*, Li Li, Zhanguo Wang, and Lin Wang, Synthesis of
Benzo[1,4]oxazin-3-one-based Diverse Compounds Using 1, 5-Difluoro-2, 4-dinitrobenzene, J. Combi. Chem. 2007, 9, 158-170.
86. Tian-Ming Yang, Gang Liu*, Solution-Phase Parallel Synthesis of 3-
Substituted Indolin-2-ones, J. Combi. Chem. 2007, 9, 86-95.
87. Gang Liu*, Li Li, Binbin Kou, Suode Zhang, Liang Zhang, Yunyun Yuan, Tao
Ma, Yan Shang, and Yuancheng Li, Benzofused Tricycles Based On 2- Quinoxalinol, J. Combi. Chem. 2007, 9, 70-78.
88. Bin-Bin KOU, Fa ZHANG, Tian-Ming YANG, Gang LIU*, Simultaneous
Solid-Phase Synthesis of Quinoxalinone and Benzimidazole Scaffold Libraries,
J. Combi. Chem. 2006, 8, 841-847.
89. A. Salomé Veiga, Yunyun Yuan, Xuqin Li, Nuno C. Santos, Gang Liu*,
Miguel A. R. B. Castanho*, Why are HIV-1 fusion inhibitors not effective
against SARS-CoV- Biophysical evaluation of molecular interactions,
Biochimica et Biophysica Acta (BBA) - General Subjects, 2006, 1760(1), 55-
61.
90. Hongbo Hu, Li Li, Richard Y. Kao, Binbin Kou, Zhanguo Wang, Liang Zhang, Huiyuan Zhang, Zhiyong Hao, Wayne H. Tsui, Anping Ni, Lianxian Cui, Baoxing Fan, Feng Guo, Shuan Rao, Chengyu Jiang, Qian Li, Manji Sun, Wei
He*, Gang Liu*, Screening and Identification of Linear B-cell Epitopes and
Entry Blocking Peptide of Severe Acute Respiratory Syndrome (SARS)
Associated Coronavirus Using Synthetic Overlapping Peptide Library, J.
Combi. Chem. 2005, 7, 648-656.
91. Jiang Zhang, Liang Zhang, Suode Zhang, Gang Liu*，Solution-Phase Parallel Synthesis of a Novel 1,2,7-trialkyl-1H-imidazo[4,5-g]quinoxalin-6-ol Library Scaffold, J. Combi. Chem. 2005, 7, 657-664.
92. Hong-Zhen Yang, Song Xu, Xue-Yan Liao, Suo-De Zhang, Zheng-Lun Liang, Bai-He Liu, Jin-Ye Bai, Chao Jiang, Jian Ding, Gui-Fang Cheng*, Gang Liu*, A novel immunostimulator, N2-[-O-benzyl-N-(acetylmuramyl)-L-alanyl-D-isoglutaminyl]-N6-trans-(m-nitrocinnamoyl)-L-lysine (MDP-C), and its
adjuvancy on the hepatitis B surface antigen, J. Med. Chem. 2005, 48, 5112-
5122.
93. Nian-Huan Yao, Gang Liu*, Wen-Yi He, Changqun Niu, James R. Carlson,
Kit S. Lam, Solid-phase synthesis and antibacterial evaluations of N-demethylvancomycin derivatives, Bioorg. Med. Chem. Lett. 2005, 15(9):
2325-2329.
94. Nian-Huan Yao, Wen-Yi He, Kit S. Lam, and Gang Liu*, Conformational
Studies of Resin-Bound Vancomycin and The Complex of Vancomycin and
Ac2-L-Lys-D-Ala-D-Ala, J. Combi. Chem. 2005, 7, 123-129.
95. Li Li, Gang LIU*, Zhanguo Wang, Yunyun Yuan, Chunxu Zhang, Xianghong
Wu, Jing Zhang, Multi-step parallel synthesis of substituted 5-aminobenzimidazoles in solution-phase, J. Combi. Chem. 2004, 6, 811-821.
96. Nian-Huan YAO, Wen-Yi HE, Kit S. LAM, Gang LIU*, Solid-Phase Synthesis of O-glycosylated N-Fmoc Amino Acids and Analysis By The High Resolution Magic Angle Spinning NMR (HR/MAS NMR), J. Combi. Chem.
2004, 6, 214-219.
97. Xin-Mei Zhang, Gang Liu, Man-Ji Sun*, Anti-epitope antibody, a novel site-directed antibody against human acetylcholinesterase, Acta Pharmacol. Sin.2004, 25(4): 431-435.
98. Liang ZHANG, Gang LIU*, Suo-De ZHANG, Xiang-Hong WU, Hong-Zhen
YANG, Li LI, Gang-Chun SUN, Bin-Bin KOU, Song XU, Ya-Fei JI, Gui-Fang
CHENG, Parallel approach for solution-phase synthesis of 2-quinoxalinol
analogues and their inhibition of LPS-induced TNF- release on mouse
macrophage in vitro, J. Combi. Chem. 2004, 6, 431-436.
99. Xiang-Hong Wu, Gang Liu*, Jing Zhang, Zhan-Guo Wang, Song Xu, Suo-De
Zhang, Liang Zhang, Lin Wang, Solution-phase reductive cyclization of 2-
quinoxalinol analogs: systematic study of parallel synthesis, Mol. Divers. 2004,
8 (2): 165-174.
100. Zhang Xing-mei, Li Qian, Wu Jun-hua, Shao Ning-sheng, Liu Gang, Sun
Man-ji*, Specific oligobodies against human brain acetylcholinesterase", Brain
Research 2003, 989; 2: 147-151.
101. 贺文义，姚念环，LAM , Kit S.，刘刚*, 高分辨魔角核磁共振技术
（HR/MAS）在固相合成中的应用，波谱学杂志 2003, 20(2): 201-208。
102. LIU XM, ZHANG DJ, CAO GJ, YANG G, DING HM, LIU G, FAN M,
SHEN BF and SHAO NS*, RNA Aptamers Specific for Bovine Thrombin,
Journal of Molecular Recognition 2003, 16:23-27.
103. 刘刚*，范业梅，赵占工，Kit S LAM， “一珠一化合物”组合化学方法
筛选抗万古霉素耐药菌活性化合物，中国药物化学杂志 2002，12（6）：
311-318。
104. Nagy SR, Liu G, Lam KS, Denison MS*, Identification of Novel Ah
Receptor Agonists Using a High-Throughput Green Fluorescent Protein-Based Recombinant Cell Bioassay, Biochemistry 2002, 41(3): 861-868.
105. Suo-De ZHANG, Gang LIU*, Shu-Quan XIA, Ping WU, Liang ZHANG,
“Meshed-Bag Gathered-Bunch” method for solid-phase synthesis of small
molecular diverse compounds, J. Combi. Chem. 2002, 4, 131-137. (Google
citation: 15, 20180115)
106. Suo-De ZHANG, Gang LIU*, Su-Quan XIA, Ping WU, Design and
synthesis of muramyl dipeptide cyclic analogue, Chinese Chemical Letters
2002, 13(1), 17-18.
107. Suo-De ZHANG, Gang LIU*, Su-Quan XIA, Design and solid-phase
synthesis of multiple muramyl dipeptide(MMD), Chinese Chemical Letters
2001, 12(10): 887-888.
108. Xin-Mei ZHANG, Gang LIU, Man-Ji SUN*, Cross-immunoreactivity of
synthetic antigenic decapeptides of human brain acetylcholinesterase with anti-Torpedo acetylcholinesterase polyclonal antibodies, Brain Research 2001,
895(1-2): 277-282.
109. Xin-Mei ZHANG, Gang LIU, Man-Ji SUN*, Epitopes of human brain
Acetylcholinesterase, Brain Research 2000, 868: 157-164.
110. Gang LIU, Ye-Mei FAN, James R. CALSON, and Kit S. LAM*, Solution-phase synthesis of 1,5-dialkylamino-2,4-dinitrobenzene library and the identification of novel antibacterial compounds from this library, J. Combi.
Chem. 2000, 2(5), 467-474.
111. Gang LIU*, Shuo-De ZHANG, Shu-Quan XIA, and Zhen-Kai DING,
Solid-phase synthesis of muramyl dipeptide derivatives using Multipin method, Bioorg. Med. Chem. Lett. 2000, 10, 1361-1363.
112. Gang LIU*, Shao-Feng MU, Liu-Hong YUN, Zhen-Kai DING, Man-Ji
SUN, Systematic studies of the substituted active C-terminus of hirudin,
Journal of Peptide Research 1999, 54(6), 480-490.
113. Gang LIU, and Kit S. LAM, “One-bead, one-compound” combinatorial
library method, In Fenniri(Ed.), Combinatorial Chemistry: a practice protocol
approach, pp 33-50, Oxford University Press, Oxford.
114. Gang LIU, Yemeif Ye, De-Zheng ZHAO, Kit S. LAM, Development of
novel peptide antibiotics for vancomycin resistant infection using the “One-bead, one-compound” combinatorial library method, In G. B. Fields, J. P. Tam & G. Barany(Eds.), Peptide for the new millennium, 2000, pp. 736-737,
Kluwer Academic Publicher, Dordrecht.
115. Gang LIU, Shao-Feng Mu, Liu-Hong YUN, Zhen-Kai DING, Yu-Long
CONG, Zhong-Jian YIN, Anticoagulative activity of synthetic C-terminus of
desulfo hirudin and analogous, 中国药物化学杂志，1998，8（1），14-18。
116. Shuo-De ZHANG, Gang LIU*, Shu-Quan XIA and Zheng-Kai DING,
Parallel synthesis of muramyl peptide derivatives, in Proceeding of the 1998
Chinese peptide symposium, Peptides: Biology and Chemistry, Eds. Xiao-Yu
HU, Rui WANG and James P. TAM, pp 198-201, Kluwer Acadeic Publisher,
Dordrecht.
117. LIU, G., MU S. F., YUN L. H., DING Z. K.; SUN M. J., Systematic study
of the substituted active C-terminus of hirudin with nature amino acids, Book
of Abstracts, 213th ACS National Meeting, San Francisco, April 13-17(1997),
MEDI-115. Publisher: American Chemical Society, Washington, D. C.
118. Li GUO, Gang LIU*, and Liu-Hong YUN, Simultaneous synthesis of
hirudin analogs containing N-substituted-glycine using the Multipin method, 中国药物化学杂志 1997, 7(1), 43-45.
119. Gang LIU, Jian-Xin WANG, and Zhen-Kai DING, Simultaneous synthesis
of peptoid(N-substituted glycine) using Multipin method, 有机化学 1996，
16，445-449。
120. Gang LIU, Jian-Xin WANG, Li GUO, Shuo-De ZHANG, Liu-Hong YUN,
Shu-Quan XIA, and Zhen-Kai DING, Simultaneous multiple peptide synthesis
using the Multipin method, 药学学报 1996，31(8), 591-596。
121. Gang LIU, Zhen-Lun LIANG, Meng-Shen CAI, Hui ZHUANG, Jian-Ping
GUO, and Qi-Min TAO, Studies on synthetic peptide XX, the synthetic peptide
antigenicity and linear epitope map of hepatitis C virus, 药学学报 1996，5，
358。
122. Gang LIU, Zhen-Lun LIANG, Meng-Shen CAI, Hui ZHUANG, Jian-Ping
GUO, and Qi-Min TAO, Studies on synthetic peptide XIX, Hepatitis C
virus(HCV) immune selection, 药学学报 1996，31（10），751-756。
123. Zheng-Lun LIANG, Gang LIU, Meng-Shen CAI, Hui ZHUANG, Using a
synthetic peptides of anti-HCV core in serodiagnosis of HCV infection, 中国公共卫生杂志 1994，13(2)：77-78。
124. Zheng-Lun LIANG, Gang LIU, Meng-Shen CAI, Hui ZHUANG ， A
studying of antigenicity and immunogenicity of synthetic peptides derivatives
from hypervariable regions of Hepatitis C virus, 中国卫生公共杂志 1995，
14(3)：135-137。
125. WANG T. X., ZHUANG H., LI H. M., FAN J. S., QI Z. B., LIU G.,
Detection of GBV-C infection and sequencing of partial gene of a Chinese
strain of GBV-C, 中国微生物免疫学杂志 1996，16(4)：263-266。
126. Shuo-De ZHANG, Gang LIU*, Shu-Quan XIA, and Zhen-Kai DING, Solid
phase synthesis of N-acetylmuramyl-L-alanyl-D-isoglutamine(MDP) analogs
using Multipin method, 中国国际多肽学术研讨会 1996(CPS-96)，July,
Cheng Du, China。
127. Gang LIU, Zhen-Lun LIANG, Meng-Shen CAI, and Hui Zhuang，Studies
on synthesis of HCV vaccine I: design, chemical synthesis and antigenicity of
peptide fragments of HCV, Proceeding of the 1994 Chinese and International
Peptide Symposium, Peptides: Biology and Chemistry, ESCOM, Leiden 1995,
241-244。
128. Gang LIU, Zhen-Lun LIANG, Meng-Shen CAI, and Hui Zhuang, Studies
on synthesis of HCV vaccine II: Hepatitis C virus(HCV) immune selection,
Proceeding of the 1994 Chinese International Peptide Symposium, Peptides:
Biology and Chemistry, ESCOM, Leiden 1995, 248-250。
129. Gang LIU, An-Bang WANG, Meng-Shen CAI, Improved synthesis of
immunoadjuvant N-acetylmuramyl dipeptide and analogs, 第五届中国天然产物化学学术研讨会，1993，144。
130. 刘刚，管关金，何敬言，刘文清, 连续反应生产氯化石蜡-52 的研究,
辽宁化工 1991，2，51。
131. 刘刚, 刘文清, Synthesis of 7-octylenic acid--butyllactone, 化学与粘和1991，2，8。
132. 刘刚, Successive produce chlorowax in three column, 天然气化工 1990，
19(6)，427。
133. Gang LIU, Wen-Qing LIU, Synthesis of glycdiol ether-thermostablizater
for chlorowax with phase-transition catalyst, 化学与粘和 1991，2，89。
134. 刘刚，管关金，相转移催化合成氯化石蜡热稳定剂缩水甘油醚，化学
与粘合，1989，4，238-239.
135. 刘刚，管关金，刘文清,麦芽酚和乙基麦芽酚的合成, 化学工程师
1989，6，29。
136. 刘刚，刘文清, 利用 1,4-二氯甲氧基丁烷氯甲基化交联聚苯乙烯
(Chloromethylated cross-linked polystyrene by using of
dichloromethoxybutane), 黑龙江化工 1987，4。
