部分学术论文 共75篇
[1]. Weiyi Zheng, Jie Gao, Man Zhang, Wenjuan Liu, Xiaoyao Ma, Wei Lei, Xiaotao Hou, Erwei Hao,
Yuanyuan Hou*, Gang Bai*. Cinnamaldehyde enhances anti-melanoma activity through covalently binding ENO1 and have synergy effects with dacarbazine. Cancer, 2020, 12: 311.
[2]. Zhihua Wang, Wenbo Wu, Elaine Leung, Chenxiang Guan, Shuang Guo, Chaowen Li, Ruixue Niu, Min Jiang, Yuanyuan Hou*, Zhihong Jiang*, Gang Bai*. 20(S)-Protopanaxatriol promotes the binding of P53 and DNA to regulate the antitumor network via multiomic analysis. Acta Pharmaceutica Sinica B, 2020, 10(6):1020-1035.
[3]. Chuanjing Cheng, Fukui Shen, Guoyu Ding, Aina Liu, Simeng Chu, Yuejiao Ma, Xiaotao Hou, Erwei Hao, Xiaoying Wang, Yuanyuan Hou*, Gang Bai*. Lepidiline A Improves the Balance of Endogenous Sex Hormones and Increases Fecundity by Targeting HSD17B1. Molecular Nutrition & Food Research, 2020, 64, 19007062020.
[4]. Simeng Chu, Wenjuan Liu, Yujie Lu, Menglin Yan, Yingying Guo, Nianwei Chang, Min Jiang*, Gang Bai*. Sinigrin Enhanced Anti-asthmatic Effects of beta-Adrenergic Receptors Agonists by Regulating cAMP-Mediated Pathways. Frontiers in Pharmacology, 2020, 11:723.
[5]. Man Zhang; Xiaoyao Ma; Honglei Xu; Wenbo Wu; Xiaoying Wang; Min Jiang; Yuanyuan Hou*; Gang Bai*. A natural AKT inhibitor swertiamarin that targets the AKT-PH domain inhibits downstream signaling and alleviates inflammation. FEBS Journal, 2020, 287(9):1816-1829.
[6]. Weiyi Zhang, Jie Gao, Fukui Shen, Xiaoyao Ma, Zhihua Wang, Xiaotao Hou, Erwei Hao, Yuanyuan Hou, Gang Bai*. Cinnamaldehyde changes the dynamic balance of glucose metabolism by targeting ENO1. Life sciences, 2020, 258, 118151.
[7]. Man Zhang, Lili Ye, Hao Huang, Dandan Cheng, Wenbo Wu, Kaixin Liu, Zhihong Jiang, Yuanyuan Hou*, Gang Bai*. Micelles self-assembled by 3-O-β-D-glucopyranosyl latycodigenin enhances cell membrane permeability, promotes antibiotic pulmonary targeting and improves anti-infect efficacy. Journal of Nanobiotechnology, 2020, 18:140.
[8]. Nianwei Chang, Jie Gao, Lin Niu, Yuanyuan Hou, Min Jiang*, Gang Bai*. Integrated artificial neural network analysis and functional cell based affinity mass spectrometry for screening a bifunctional activator of Ca2+ and β2AR in Aconite. Journal of Pharmaceutical and Biomedical Analysis, 2020, 190: 113506.
[9]. Jia-gang Deng, Xiao-tao Hou, Tie-jun Zhang, Gang Bai, Er-wei Hao, Justin Jang Hann Chu, Jintanaporn Wattanathorn, PaneeSirisa-ard, Ch'ngSoo Ee, JohnLow, Chang-xiao Liu*. Carry forward advantages of traditional medicines in prevention and control of outbreak of COVID-19 pandemic. Chinese Herbal Medicines, 2020, 12 (3): 207-213.
[10]. Shengnan Yang, Yuan Zhang, Fukui Shen, Xiaoyao Ma, Man Zhang, Yuanyuan Hou*, Gang Bai*. The flavonoid baicalin improves glucose metabolism by targeting the PH domain of AKT and activating AKT/GSK3β phosphorylation. FEBS Letters. 2019, 593: 175-186.
[11]. Yunbing Shen; Shengnan Yang; Xueyan Hu; Man Zhang; Xiaoyao Ma; Zhihua Wang; Yuanyuan Hou*; Gang Bai*. Natural Product Puerarin Activates Akt and Ameliorates Glucose and Lipid Metabolism Dysfunction in Hepatic Cells. Journal of Functional Foods 2019, 55: 296-304.
[12]. Yuan Zhang, Zhihua Wang, Xiaoyao Ma, Sengnan Yang, Xueyan Hu, Yuanyuan Hou*, Gang Bai*. Glycyrrhetinic acid binds to the conserved P-loop region and interferes with the interaction of RAS-effector proteins. Acta Pharmaceutica Sinica B. 2019, 9(2):294–303.
[13]. Yuan Zhang, Shengnan Yang, Man Zhang, Zhihua Wang, Xin He, Yuanyuan Hou, Gang Bai*. Glycyrrhetinic acid improves insulin resistance by regulating the balance between the Ras/MAPK and PI3K/Akt pathways. Nutrients 2019, 11, 604.
[14]. Yujie Lu, Wenjuan Liu, Man Zhang, Yanfang Deng, Min Jiang*, Gang Bai*. The Screening Research of NF-κB inhibitors from Moutan Cortex Based on Bioactivity-integrated UPLC-Q/TOF-MS. Evidence-based Complementary and Alternative Medicine 2019, 6150357.
[15]. Fang Ma, Qingxin Cui*, Gang Bai. Combined with UPLC/Q-TOF-MS/MS and bioactivity assay for NF-κB inhibitors identification in uyghur medicine Althaea rosea flowers. Frontiers in Plant Science 2019, 9, 1975.
[16]. Jianan Ni, Yingying Guo, Nianwei Chang, Menglin Yan, Dandan Cheng, Min Jiang*, Gang Bai*. Effect of N-methyltyramine on the regulation of adrenergic receptors via enzymatic epinephrine synthesis for the treatment of gastrointestinal disorders. Biomedicine & Pharmacotherapy 2019, 111: 1393-1398.
[17]. Zhihua Wang, Unchol Kim, Yanting Jiao, Chaowen Li, Yingying Guo, Xiaoyao Ma, Min Jiang, Zhihong Jiang, Yuanyuan Hou*, Gang Bai*. Quantitative Proteomics Combined with Affinity MS Revealed the Molecular Mechanism of Ginsenoside Antitumor Effects. Journal of Proteome Research 2019, 18, 2100-2108.
[18]. Yujie Lu, Yanfang Deng, Wenjuan Liu, Min Jiang*, Gang Bai*. Searching for Calcium Antagonists for Hypertension Disease Therapy from Moutan Cortex, using Bioactivity Integrated UHPLC-Q/TOF-MS. Phytochemical analysis. 2019, 30:456-4632019.
[19]. Qingyang Xu, Fang Bai, Ning Chen, Gang Bai*. Utilization of acid hydrolysate of recovered bacterial cell as a novel organic nitrogen source for L-tryptophan fermentation. Bioengineered. 2019; 10(1):23-32.
[20]. Lee-Fong Yau, Ju Liu, Min Jiang, Gang Bai, Jing-Rong Wang*, Zhi-Hong Jiang. An integrated approach for comprehensive profiling and quantitation of IgG-Fc glycopeptides with application to rheumatoid arthritis. Journal of Chromatography B 2019, 1122-1123: 64-72.
[21]. Xiaoyao Ma, Aina Liu, Wenjuan Liu, Zhihua Wang, Nianwei Chang, Suyun Li, Jiansheng Li, Yuanyuan Hou*, Gang Bai*. Analyze and identify Peiminine target EGFR improve lung function and alleviate pulmonary fibrosis to prevent exacerbation of COPD by phosphoproteomics analysis. Frontiers in Pharmacology. 2019, 10:737.
[22]. Wenjuan Liu, Yujie Lu, Simeng Chu, Min Jiang*, Gang Bai*. Phillygenin, a lignan compound,inhibits hypertension by reducing PLCβ3-dependent Ca2+ oscillation. Journal of Functional Foods. 2019, 60: 103432.
[23]. Zhihua Wang, Unchol Kim, Jinbiao Liu, Chuanjing Cheng, Wenbo Wu, Shuang Guo, Yunjiang Feng, Ronald J. Quinn, Yuanyuan Hou*, Gang Bai*. Comprehensive TCM molecular networking based on MS/MS in silico spectra with integration of virtual screening and affinity MS screening for discovering functional ligands from natural herbs. Analytical and Bioanalytical Chemistry. 2019, 411(22):5785–5797.
[24]. Wei Lei, Yan-Fang Deng, Xiao-Yao Ma, Jia-nan Ni, Min Jiang*, Gang Bai*. Phthalides, senkynolide A and ligustilide, show immunomodulatory effect in improving atherosclerosis, by suppressing CD137 expression. Biomedicine & Pharmacotherapy. 2019, 117:109074.
[25]. Fukui Shen, Wenbo Wu, Man Zhang, Zhongyao Tang, Hao Huang, Jingrong Wang, Zhihong Jiang, Yuanyuan Hou*, Gang Bai*. Micro-PET Imaging Demonstrates 3-O-β-D-Glucopyranosyl Platycodigenin as an Effective Metabolite Affects Permeability of Cell Membrane and Improves Dosimetry of [18F]-Phillygenin in Lung Tissue. Frontiers in Pharmacology. 2019, 10:1020.
[26]. Qingxin Cui, Fang Ma, Jin Tao, Min Jiang*, Gang Bai, Guoan Luo. Efficacy Evaluation of Qingyan Formulation in a Smoking Environment and Screening of Anti-inflammatory Compounds. Biomedicine & Pharmacotherapy. Biomedicine & Pharmacotherapy. 2019, 118: 109315.
[27]. Hua Luo, Erwei Hao, Dechao Tan, Wei Wei, Jinling Xie, Xiaohui Feng, Zhengcai Du, Chunying Huang, Gang Bai, Yuanyuan Hou, Chuanjing Cheng, Xiangxi Yi, Yitao Wang, Xiaotao Hou*, Jiagang Deng*. Apoptosis effect of Aegiceras corniculatum on human colorectal cancer via activation of FoxO signaling pathway. Food and Chemical Toxicology, 2019, 134: 110861.
[28]. Yanting Jiao, Fukui Shen, Zhihua Wang, Lili Ye, Yuanyuan Hou*, Gang Bai*. Genipin, a natural AKT inhibitor, targets the PH domain to inhibit inflammation. Biochemical Pharmacology 2019, 170: 113660.
[29]. Kaixue Zhang, Menglin Yan, Shu Han, Longfei Cong, Liyao Wang, Liu Zhang, Lili Sun, Haiying Bai, Guanhua Wei, Hong Du, Min Jiang, Gang Bai, Zhigang Yang*. Identification of Chemical Markers for the Discrimination of Radix Angelica sinensis Grown in Geoherb and Non-Geoherb Regions Using UHPLC-QTOF-MS/MS Based Metabolomics. Molecules. 2019, 24(19): 3536.
[30]. Qingxin Cui, Yang Liu, Mengge Zhou, Yanqi Han, Chengcheng Yin, Gang Bai*. An optimized microPET imaging method for the distribution and synergies of natural products. Frontiers in Pharmacology, 2018, 9: 948.
[31]. Jie Gao, Xin He, Yuejiao Ma, Xuezhi Zhao, Xiaotao Hou, Erwei Hao, Jiagang Deng, Gang Bai*.Chlorogenic Acid Targeting of the AKT PH Domain Activates AKT/GSK3β/FOXO1 Signaling and Improves Glucose Metabolism. Nutrients, 2018, 10: 1366.
[32]. Wei Lei, Jianan Ni, Xueting Xia, Min Jiang, Gang Bai*. Searching for synergistic calcium antagonists and novel therapeutic regimens for coronary heart disease therapy from a Traditional Chinese Medicine, Suxiao Jiuxin Pill. Journal of Chromatography B, 2018, 1092: 220-227.
[33]. Gang Bai, Tiejun Zhang, Yuanyuan Hou, Guoyu Ding, Min Jiang, Guoan Luo. From quality markers to artificial intelligence assessment: a smart quality-evaluation strategy for traditional Chinese medicine based on quality markers. Phytomedicine, 2018, 44: 109-116.
[34]. Xueyan Hu, Yunbing Shen, Shengnan Yang, Wei Lei, Cheng Luo, Yuanyuan Hou, Gang Bai. Metabolite identification of ursolic acid in mouse plasma and urine after oral administration by ultra-high performance liquid chromatography/quadrupole time-of flight mass spectrometry. RSC Advances, 2018, 8: 6532-6539.
[35]. Mengge Zhou, Xiaoyao Ma, Guoyu Ding, Zengyong Wang, Dan Liu, Yongling Tong, Hong Zhou, Jie Gao, Yuanyuan Hou, Jiang Min, Bai Gang*. Comparison and evaluation of antimuscarinic and anti-inflammatory effects of five Bulbus fritillariae species based on UPLC-Q/TOF integrated dual-luciferase reporter assay, PCA and ANN analysis. Journal of Chromatography B, 2017, 1041-1042: 60–69.
[36]. Nianwei Chang, Yanmei Li, Mengge Zhou, Jie Gao, Yuanyuan Hou, Min Jiang, Gang Bai*. The hemostatic effect study of Cirsium setosum on regulating α1-ARs via mediating norepinephrine synthesis by enzyme catalysis. Biomedicine & Pharmacotherapy, 2017, 87: 698-704.
[37]. Zengyong Wang, Qian Wang, Yan-Qi Han, Min Jiang, Jie Gao, Yan Miao, Gang Bai*. Bioactivity-based UPLC/Q-TOF/MS strategy for screening of anti-inflammatory components from Cimicifugae Rhizoma. Chinese chemical letters, 2017, 28: 476-481.
[38]. Zengyong Wang, Yu Cui, Guoyu Ding, Mengge Zhou, Xiaoyao Ma, Yuanyuan Hou, Min Jiang, Dailin Liu, Gang Bai*. Mahuannin B an adenylate cyclase inhibitor attenuates hyperhidrosis via suppressing β2-adrenoceptor/cAMP signaling pathway. Phytomedicine, 2017, 30: 18-27.
[39]. Qingxin Cui, Yuanyuan Hou, Yanan Wang, Xu Li, Yang Liu, Xiaoyao Ma, Zengyong Wang, Weiya Wang, Jin Tao, Qian Wang, Min Jiang, Dongyan Chen, Xizeng Feng, Gang Bai*. Biodistribution of arctigenin-loaded nanoparticles designed for multimodal imaging. Journal of Nanobiotechnology, 2017, 15(1): 27.
[40]. Zengyong Wang, Qian Wang, Guoyu Ding, Min Jiang, Gang Bai*. Cimicifugamide from Cimicifuga rhizomes functions as a nonselective β-AR agonist for cardiac and sudorific effects. Biomedicine & Pharmacotherapy, 2017, 90: 122-130.
[41]. Guoyu Ding, Yanshuai Wang, Aina Liu, Yuanyuan Hou, Tiejun Zhang, Gang Bai*, Changxiao Liu. From chemical markers to quality markers: An integrated approach of UPLC/Q-TOF, NIRS and chemometrics for the quality assessment of honeysuckle buds. RSC Advances, 2017, 7(36): 22034-22044.
[42]. Qingyang Xu, Fang Bai, Ning Chen, Gang Bai*. Gene modification of the acetate biosynthesis pathway in Escherichia coli and implementation of the cell recycling technology to increase L-tryptophan production. PLoS One, 2017, 12(6): e0179240.
[43]. Yanmei Li, Nianwei Chang, Yanqi Han, Mengge Zhou, Jie Gao, Yuanyuan Hou, Min Jiang, Tiejun Zhang, Gang Bai. Anti-inflammatory effects of Shufengjiedu Capsule for upper respiratory infection via the ERK pathway. Biomedicine & Pharmacotherapy, 2017, 9(94): 758-766.
[44]. Zhongyao Tang, Yuanyuan Hou*, Xueyan Hu, Aina Liu, Leefong Yau, Tiantian Tong, Zhihong Jiang, Gang Bai. Metabolite identification and pharmacokinetic study of Platycodi Radix (Jiegeng). RSC Advances, 2017, 7 (59): 37459-37466.
[45]. Jie Gao, Shengtao Lv, Changzhi Li, Jin Tao, Chengqi Jia, Min Jiang, Yuanyuan Hou, Xiaotao Hou, Jiagang Deng, Gang Bai*. Bioactivity-based antioxidative components screening and evaluation in grape seed proanthocyanidin extract. Journal of Food Science and Technology, 2017, 54(9): 2645–2652.
[46]. Liu wenjuan, Chu Guangcui, Chang Nianwei, Xiaoyao Ma, Jiang Min, Bai Gang*. Phillygenin attenuates inflammatory responses and influences glucose metabolic parameters by inhibiting Akt activity. RSC Advances, 2017, 7(64): 40418–40426.
[47]. Xiaoyao Ma, Yuan Zhang, Zengyong Wang, Yunbing Shen, Man Zhang, Quandeng Nie, Yuanyuan Hou, Gang Bai*. Ursolic acid, a natural nutraceutical agent target to caspase3 alleviates inflammatory associated downstream signal transduction process. Molecular nutrition & food research, 2017, 61, 1700332.
[48]. Mengge Zhou, Xiaoyao Ma, Jixue Sun, Guoyu Ding, Qingxin Cu, Yan Miao, Yuanyuan Hou, Min Jiang, Gang Bai*. Active fragments-guided drug discovery and design of selective tropane alkaloids using ultra-high performance liquid chromatography-quadrupole time-of-flight tandem mass spectrometry coupled with virtual calculation and biological evaluation. Analytical Bioanalytical Chemistry, 2017, 409: 1145-1157.
[49]. Dan Sun, Yanqi Han, Weiya Wang, Zengyong Wang, Xiaoyao Ma, Yuanyuan Hou, Gang Bai. Screening and identification of Caulis Sinomenii bioactive ingredients with dual-target NF-κB inhibition and 2-AR agonizing activities. Biomedical Chromatography, 2016, 30(11): 1843-1853.
[50]. Jin Tao, Yuanyuan Hou, Xiaoyao Ma, Dan Liu, Yongling Tong, Hong Zhou, Jie Gao, Gang Bai. An integrated global chemomics and system biology approach to analyze the mechanisms of the traditional Chinese medicinal preparation Eriobotrya japonica – Fritillaria usuriensis dropping pills for pulmonary diseases. BMC Complementary and Alternative Medicine, 2016, 16(1): 4.
[51]. Zheng Yang, Zhiqiang Lu, Yanjun Zhang, Yubo Li, Zengyong Wang, Yanling Zhang, Pengwei Zhuang, Gang Bai. Looking for agonists of β2 adrenergic receptor from Fuzi and Chuanwu by virtual screening and dual-luciferase reporter assay. Journal of Asian Natural Products Research, 2016, 18(6): 550-561.
[52]. Qingxin Cui, Min Fu, Mengge Zhou, Nianwei Chang, Ye Pan, Min Jiang, Zengtao Sun, Gang Bai. Bioactivity-based ultra-performance liquid chromatography-coupled quadrupole time-of-flight mass spectrometry for NF-κB inhibitors identification in Chinese Medicinal Preparation Bufei Granule. Biomedical Chromatography, 2016, 30(8): 1184-1189.
[53]. Guoyu Ding, Yuanyuan Hou, Yanqi Han, Jingru Zhang, Aina Liu, Zenghui Liu, Jiamin Peng, Min Jiang, Gang Bai. A rapid score evaluation system based on near infrared spectroscopy for quality control of Flos Chrysanthemi. Journal of Pharmaceutical and Biomedical Analysis, 2016, 131: 391-399.
[54]. Jin Tao, Yan Nie, Yuanyuan Hou, Xiaoyao Ma, Guoyu Ding, Jie Gao, Min Jiang, Gang Bai. Chemomics-Integrated Proteomics Analysis of Jie-Geng-Tang to Ameliorate Lipopolysaccharide-Induced Acute Lung Injury in Mice. Evidence-Based Complementary and Alternative Medicine, 2016, 2016(19): 1-12.
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