个人简介
Since my childhood, I have been fascinated by two questions:1 why human can do intelligent things that computers cannot do. 2 what is a good life. I am glad that I found out that I can tackle these fundamental questions with the tools provided by modern neuroscience, and this incredible interdisplinary field of brain research provides many exciting opportunities. Since coming to Tsinghua, I have also been increasingly interested in brain related medical problems, like depression and anxiety disorders, which challenge us and makes life difficult for many people. The overarching theme in my lab is what I call connectomics and functional connectomics, where we take inspiration from genomics and functional genomics to aim at arriving at a circuit diagram of the brain and relate circuit structures to their functions and elucidate the computational processes carried out by those circuits.
部分学术论文 共11篇
Chenggang Chen, Mingxiu Cheng, Tetsufumi Ito, Sen Song*. Neuronal organization in the inferior colliculus revisited with cell-type-dependent monosynaptic tracing, Journal of Neuroscience. 28 March 2018, 38 (13) 3318-3332.
Chen Zhu, Yun Yao, Yan Xiong, Mingxiu Cheng, Jing Chen, Rui Zhao, Fangzhou Liao, Runsheng Shi, Sen Song*. Somatostatin Neurons in the Basal Forebrain Promote High-Calorie Food Intake. Cell Reports, 2017, Volume 20 , Issue 1 , 112 – 123.
Song S&*, Grillo FW&, Xi J, Ferretti V, Gao G, De Paola, V.* (2015) EPBscore: a Novel Method for Computer-Assisted Analysis of Axonal Structure and Dynamics. NeuroInformatics (co-first and co-corresponding author)
Wang Q, Zhang J, Song S*, Zhang Z*. (2014) Attentional Neural Network: Feature Selection Using Cognitive Feedback. Advances in Neural Information Processing Systems, 2033-2041.
Sumbul U*, Song S*, McCulloch K, Becker M, Lin B, Sanes JR, Masland R, Seung SH. (2014) A genetic and computational approach to structurally classify neuronal types. Nature Communications, 5:3512.
Canty AJ, Ruivo LMTG, Nesarajah C, Song S, Jackson JS, Little GE, De Paola,V* (2013) Synaptic elimination and protection after minimal injury depend on cell type and their prelesion structural dynamics in the adult cerebral cortex. The Journal of Neuroscience 33 (25), 10374-10383.
Grillo, F.W., Song, S*, Ruivo, LMTG., Huang,L., Gao, G., Knott, GW., Maco, B., Ferretti, V., Thompson, D., Graham,L., De Paola,V. (2013) Increased axonal bouton dynamics in the ageing mouse cortex. PNAS, 110(16), E1514-23.
Song S&, Liu L&, Edwards SV, Wu S* (2012) Resolving conflict in eutherian mammal phylogeny using phylogenomics and the multispecies coalescent model. PNAS, 109(37) 14942-14947
Song, S.*, Sjstrm, PJ., Reigl, M., Nelson, S., Chklovskii, DB. (2005) Highly nonrandom features of synaptic connectivity in local cortical circuits. PLoS Biology 3:e68.
Song, S*., Abbott, LF. (2001) Column and map development and cortical remapping through spike-timing dependent plasticity. Neuron 32:339-50.
Song, S.*, Miller, K., Abbott, LF. (2000) Competitive Hebbian learning through spike-timing-dependent synaptic plasticity. Nature Neuroscience 3:919-926.
